Characterization of SNARE proteins in human pituitary adenomas: targeted secretion inhibitors as a new strategy for the treatment of acromegaly?

CONTEXT: Targeted secretion inhibitors (TSIs), a new class of recombinant biotherapeutic proteins engineered from botulinum toxin, represent a novel approach for treating diseases with excess secretion. They inhibit hormone secretion from targeted cell types through cleavage of SNARE (soluble N-ethy...

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Bibliographic Details
Main Authors: Garcia, E, Trivellin, G, Aflorei, E, Powell, M, Grieve, J, Alusi, G, Pobereskin, L, Shariati, B, Cudlip, S, Roncaroli, F, Mendoza, N, Grossman, AB, Harper, E, Korbonits, M
Format: Journal article
Language:English
Published: 2013