Identification of a novel AU-rich-element-binding protein which is related to AUF1.

The AU-rich element (ARE) is an important instability determinant for a large number of early-response-gene mRNAs. AREs also mediate the stabilization of certain pro-inflammatory mRNAs, such as tumour necrosis factor (TNF)-alpha and cyclo-oxygenase-2 (COX-2), in response to inflammatory stimuli. To...

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Detalles Bibliográficos
Autores principales: Dean, J, Sully, G, Wait, R, Rawlinson, L, Clark, A, Saklatvala, J
Formato: Journal article
Lenguaje:English
Publicado: 2002