Identification of a novel AU-rich-element-binding protein which is related to AUF1.
The AU-rich element (ARE) is an important instability determinant for a large number of early-response-gene mRNAs. AREs also mediate the stabilization of certain pro-inflammatory mRNAs, such as tumour necrosis factor (TNF)-alpha and cyclo-oxygenase-2 (COX-2), in response to inflammatory stimuli. To...
Autores principales: | , , , , , |
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Formato: | Journal article |
Lenguaje: | English |
Publicado: |
2002
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