The role of chromatin remodeller ATRX in gene expression

<p>ATRX is a chromatin remodeller involved in a wide range of nuclear processes, including transcription. Germline mutations in ATRX give rise to alpha- thalassaemia/intellectual disability X-linked (ATR-X) syndrome and downregulate alpha globin expression through a mechanism which is poorly u...

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Bibliographic Details
Main Author: Shen, Y
Other Authors: Gibbons, R
Format: Thesis
Language:English
Published: 2022
Subjects: