Productive folding of tyrosinase ectodomain is controlled by the transmembrane anchor.

Transmembrane domains (TMDs) are known as structural elements required for the insertion into the membrane of integral membrane proteins. We have provided here an example showing that the presence of the TMD is compulsory for the productive folding pathway of a membrane-anchored glycoprotein. Tyrosi...

Full description

Bibliographic Details
Main Authors: Popescu, C, Mares, A, Zdrentu, L, Zitzmann, N, Dwek, R, Petrescu, S
Format: Journal article
Language:English
Published: American Society for Biochemistry and Molecular Biology 2006