A quantitative analysis of the contribution of costimulation to T cell activation by the T cell receptor and chimeric antigen receptors

T cells are important immune cells that become activated to respond when they recognise antigen. T cell activation can be initiated by the engagement of the T cell receptor (TCR) with antigens presented by major histocompatibility complex (pMHC) molecules on antigen-presenting cells (APCs). In addit...

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Detalhes bibliográficos
Autor principal: Patel, AB
Outros Autores: Dushek, O
Formato: Tese
Idioma:English
Publicado em: 2023
Assuntos: