Human MAIT cells respond to and suppress HIV-1

Human MAIT cells sit at the interface between innate and adaptive immunity, are polyfunctional and are capable of killing pathogen infected cells via recognition of the Class IB molecule MR1. MAIT cells have recently been shown to possess an antiviral protective role in vivo and we therefore sought...

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Bibliografische gegevens
Hoofdauteurs: Phetsouphanh, C, Phalora, P, Hackstein, C-P, Thornhill, J, Munier, CML, Meyerowitz, J, Murray, L, VanVuuren, C, Goedhals, D, Drexhage, L, Moore, R, Sattentau, QJ, Mak, JY, Fairlie, DP, Fidler, S, Kelleher, AD, Frater, J, Klenerman, P
Formaat: Journal article
Taal:English
Gepubliceerd in: eLife Sciences Publications 2021