Proteostasis and diseases of the motor unit

The accumulation in neurons of aberrant protein species, the pathological hallmark of many neurodegenerative diseases, results from a global impairment of key cellular processes governing protein synthesis/degradation and repair mechanisms, also known as the proteostasis network (PN). The growing nu...

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Bibliographic Details
Main Authors: Rinaldi, C, Mäger, I, Wood, M
Format: Journal article
Language:English
Published: Frontiers Research Foundation 2016