Structure-Based in Silico Screening Identifies a Potent Ebolavirus Inhibitor from a Traditional Chinese Medicine Library

Potent Ebolavirus (EBOV) inhibitors will help to curtail outbreaks such as that which occurred in 2014-16 in West Africa. EBOV has on its surface a single glycoprotein (GP) critical for viral entry and membrane fusion. Recent high-resolution complexes of EBOV GP with a variety of approved drugs reve...

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Bibliographic Details
Main Authors: Shaikh, F, Zhao, Y, Alvarez, L, Iliopoulou, M, Lohans, C, Schofield, C, Padilla-Parra, S, Siu, S, Fry, E, Ren, J, Stuart, D
Format: Journal article
Language:English
Published: American Chemical Society 2019