Colchicine for COVID-19 in adults in the community (PRINCIPLE): a randomised, controlled, adaptive platform trial

Objectives Colchicine has been proposed as a COVID-19 treatment, but its effect on time to recovery is unknown. We aimed to determine whether colchicine is effective at reducing time to recovery and COVID-19 related hospitalisations/deaths among people in the community. Design Prospective, multicen...

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Những tác giả chính: PRINCIPLE Trial Collaborative Group, Dorward, J, Yu, L-M, Hayward, G, Saville, B, Gbinigie, O, Van Hecke, O, Ogburn, E, Evans, P, Thomas, NPB, Patel, M, Richards, D, Berry, N, Detry, M, Saunders, C, Fitzgerald, M, Harris, V, Shanyinde, M, de Lusignan, S, Andersson, M, Butler, C, Hobbs, FDR
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Cold Spring Harbor Laboratory Press 2021