Colchicine for COVID-19 in adults in the community (PRINCIPLE): a randomised, controlled, adaptive platform trial

Objectives Colchicine has been proposed as a COVID-19 treatment, but its effect on time to recovery is unknown. We aimed to determine whether colchicine is effective at reducing time to recovery and COVID-19 related hospitalisations/deaths among people in the community. Design Prospective, multicen...

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Bibliographic Details
Main Authors: PRINCIPLE Trial Collaborative Group, Dorward, J, Yu, L-M, Hayward, G, Saville, B, Gbinigie, O, Van Hecke, O, Ogburn, E, Evans, P, Thomas, NPB, Patel, M, Richards, D, Berry, N, Detry, M, Saunders, C, Fitzgerald, M, Harris, V, Shanyinde, M, de Lusignan, S, Andersson, M, Butler, C, Hobbs, FDR
Format: Journal article
Language:English
Published: Cold Spring Harbor Laboratory Press 2021