The effects of tetrahydrobiopterin and hyperglycaemia on macrophage metabolism in cardiovascular inflammation

<p>Macrophages are highly heterogeneous, plastic immune cells that perform a diverse spectrum of functions. Defined by their metabolic signature, macrophages stimulated by LPS/IFN-γ (M<sup>LPS/IFN-γ</sup>) display reduced oxidative phosphorylation, due to breaks in the TCA cycle, s...

Full description

Bibliographic Details
Main Author: Ayaz, F
Other Authors: Crabtree, M
Format: Thesis
Language:English
Published: 2023
Subjects: