Cytokine gene transcription of human colonic intraepithelial lymphocytes costimulated with epithelial cells bearing HLA-DR and its inhibition by 5-aminosalicylic acid.

The objectives of this study were to activate human colonic intraepithelial lymphocytes at the transcriptional level with HLA-DR+ human colonic epithelial cell line (HT29) in synergy with CD3 monoclonal antibody and to investigate the molecular mechanism for the therapeutic effects of 5-aminosalicyl...

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Bibliographic Details
Main Authors: Chen, D, Radford-Smith, G, Dipaolo, M, McGowan, I, Jewell, D
Format: Journal article
Language:English
Published: 1996