Cytokine gene transcription of human colonic intraepithelial lymphocytes costimulated with epithelial cells bearing HLA-DR and its inhibition by 5-aminosalicylic acid.
The objectives of this study were to activate human colonic intraepithelial lymphocytes at the transcriptional level with HLA-DR+ human colonic epithelial cell line (HT29) in synergy with CD3 monoclonal antibody and to investigate the molecular mechanism for the therapeutic effects of 5-aminosalicyl...
Main Authors: | Chen, D, Radford-Smith, G, Dipaolo, M, McGowan, I, Jewell, D |
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Format: | Journal article |
Language: | English |
Published: |
1996
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