Contributions of inwardly rectifying K+ currents to repolarization assessed using mathematical models of human ventricular myocytes.
Repolarization of the action potential (AP) in cardiac muscle is a major determinant of refractoriness and excitability, and can also strongly modulate excitation-contraction coupling. In clinical cardiac electrophysiology, the Q-T interval, and hence action potential duration, is both an essential...
Main Authors: | , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2006
|