Maternal high fat diet during pregnancy and lactation alters hepatic expression of insulin like growth factor-2 and key microRNAs in the adult offspring.

BACKGROUND: miRNAs play important roles in the regulation of gene functions. Maternal dietary modifications during pregnancy and gestation have long-term effects on the offspring, but it is not known whether a maternal high fat (HF) diet during pregnancy and lactation alters expression of key miRNAs...

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Bibliographic Details
Main Authors: Zhang, J, Zhang, F, Didelot, X, Bruce, K, Cagampang, F, Vatish, M, Hanson, M, Lehnert, H, Ceriello, A, Byrne, C
Format: Journal article
Language:English
Published: BioMed Central 2009