Individual differences in response to antidepressants: a meta-analysis of placebo-controlled randomized clinical trials

Individual differences in response to antidepressants: a meta-analysis of placebo-controlled randomized clinical trials

<p><strong>Importance</strong> Antidepressants are commonly used to treat major depressive disorder (MDD). Antidepressant outcomes can vary based on individual differences; however, it is unclear whether specific factors determine this variability or whether it is at random.</p&...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Maslej, MM, Furukawa, TA, Cipriani, A, Tomlinson, A, Et al.
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	American Medical Association 2021

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gan: Watanabe, N, et al.
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gan: Barbui, C, et al.
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