Effect of membrane potential on surface Ca2+ receptor activation in rat osteoclasts.
Osteoclasts are known to possess a divalent cation-sensitive receptor, the Ca2+ receptor (CaR). The latter monitors changes in the local Ca2+ concentration generated as a result of hydroxyapatite dissolution. CaR activation elevates cytosolic [Ca2+] and thereby inhibits osteoclastic bone resorption....
Main Authors: | , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
1995
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