Effect of membrane potential on surface Ca2+ receptor activation in rat osteoclasts.

Osteoclasts are known to possess a divalent cation-sensitive receptor, the Ca2+ receptor (CaR). The latter monitors changes in the local Ca2+ concentration generated as a result of hydroxyapatite dissolution. CaR activation elevates cytosolic [Ca2+] and thereby inhibits osteoclastic bone resorption....

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Bibliographic Details
Main Authors: Shankar, V, Huang, C, Adebanjo, O, Simon, B, Alam, A, Moonga, B, Pazianas, M, Scott, R, Zaidi, M
Format: Journal article
Language:English
Published: 1995