Decreased sensitivity of 5-HT(1D) receptors in melancholic depression.

BACKGROUND: Brain serotonin (5-HT) function is abnormal in major depression, but the involvement of different 5-HT receptor subtypes has been little studied. The availability of selective ligands now makes it possible to test the sensitivity of 5-HT(1D) receptors in patients with depression. AIMS:...

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Bibliographic Details
Main Authors: Whale, R, Clifford, E, Bhagwagar, Z, Cowen, P
Format: Journal article
Language:English
Published: 2001