Radiation combined with macrophage depletion promotes adaptive immunity and potentiates checkpoint blockade

Emerging evidence suggests a role for radiation in eliciting anti‐tumour immunity. We aimed to investigate the role of macrophages in modulating the immune response to radiation. Irradiation to murine tumours generated from colorectal (MC38) and pancreatic (KPC) cell lines induced colony‐stimulating...

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Bibliographic Details
Main Authors: Jones, K, Tiersma, J, Yuzhalin, A, Gordon-Weeks, A, Buzzelli, J, Im, J, Muschel, R
Format: Journal article
Published: EMBO Press 2018