Influence of soluble or matrix-bound isoforms of vascular endothelial growth factor-A on tumor response to vascular-targeted strategies

Antiangiogenic therapy based on blocking the actions of vascular endothelial growth factor-A (VEGF) can lead to "normalization" of blood vessels in both animal and human tumors. Differential expression of VEGF isoforms affects tumor vascular maturity, which could influence the normalizatio...

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Bibliographic Details
Main Authors: Akerman, S, Fisher, M, Daniel, R, Lefley, D, Reyes-Aldasoro, C, Lunt, S, Harris, S, Bjorndahl, M, Williams, L, Evans, H, Barber, P, Prise, V, Vojnovic, B, Kanthou, C, Tozer, G
Format: Journal article
Language:English
Published: 2013