Metformin improves cancer immunotherapy by directly rescuing tumor-infiltrating CD8 T lymphocytes from hypoxia-induced immunosuppression
<p><strong>Background</strong> Despite their revolutionary success in cancer treatment over the last decades, immunotherapies encounter limitations in certain tumor types and patients. The efficacy of immunotherapies depends on tumor antigen-specific CD8 T-cell viability and functi...
المؤلفون الرئيسيون: | Finisguerra, V, Dvorakova, T, Formenti, M, Van Meerbeeck, P, Mignion, L, Gallez, B, Van den Eynde, BJ |
---|---|
التنسيق: | Journal article |
اللغة: | English |
منشور في: |
BMJ Publishing Group
2023
|
مواد مشابهة
-
Metformin improves cancer immunotherapy by directly rescuing tumor-infiltrating CD8 T lymphocytes from hypoxia-induced immunosuppression
حسب: Benoit J Van den Eynde, وآخرون
منشور في: (2023-05-01) -
Enhanced tumor response to adoptive T cell therapy with PHD2/3-deficient CD8 T cells
حسب: Dvorakova, T, وآخرون
منشور في: (2024) -
Resistance to cancer immunotherapy mediated by apoptosis of tumor-infiltrating lymphocytes
حسب: Zhu, J, وآخرون
منشور في: (2017) -
Resistance to cancer immunotherapy mediated by apoptosis of tumor-infiltrating lymphocytes
حسب: Jingjing Zhu, وآخرون
منشور في: (2017-11-01) -
Enhanced tumor response to adoptive T cell therapy with PHD2/3-deficient CD8 T cells
حسب: Tereza Dvorakova, وآخرون
منشور في: (2024-09-01)