Metformin improves cancer immunotherapy by directly rescuing tumor-infiltrating CD8 T lymphocytes from hypoxia-induced immunosuppression
<p><strong>Background</strong> Despite their revolutionary success in cancer treatment over the last decades, immunotherapies encounter limitations in certain tumor types and patients. The efficacy of immunotherapies depends on tumor antigen-specific CD8 T-cell viability and functi...
Egile Nagusiak: | Finisguerra, V, Dvorakova, T, Formenti, M, Van Meerbeeck, P, Mignion, L, Gallez, B, Van den Eynde, BJ |
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Formatua: | Journal article |
Hizkuntza: | English |
Argitaratua: |
BMJ Publishing Group
2023
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