Metformin improves cancer immunotherapy by directly rescuing tumor-infiltrating CD8 T lymphocytes from hypoxia-induced immunosuppression

Metformin improves cancer immunotherapy by directly rescuing tumor-infiltrating CD8 T lymphocytes from hypoxia-induced immunosuppression

<p><strong>Background</strong> Despite their revolutionary success in cancer treatment over the last decades, immunotherapies encounter limitations in certain tumor types and patients. The efficacy of immunotherapies depends on tumor antigen-specific CD8 T-cell viability and functi...

Полное описание

Библиографические подробности
Главные авторы:	Finisguerra, V, Dvorakova, T, Formenti, M, Van Meerbeeck, P, Mignion, L, Gallez, B, Van den Eynde, BJ
Формат:	Journal article
Язык:	English
Опубликовано:	BMJ Publishing Group 2023

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