Metformin improves cancer immunotherapy by directly rescuing tumor-infiltrating CD8 T lymphocytes from hypoxia-induced immunosuppression

<p><strong>Background</strong> Despite their revolutionary success in cancer treatment over the last decades, immunotherapies encounter limitations in certain tumor types and patients. The efficacy of immunotherapies depends on tumor antigen-specific CD8 T-cell viability and functi...

詳細記述

書誌詳細
主要な著者: Finisguerra, V, Dvorakova, T, Formenti, M, Van Meerbeeck, P, Mignion, L, Gallez, B, Van den Eynde, BJ
フォーマット: Journal article
言語:English
出版事項: BMJ Publishing Group 2023