Deep immune phenotyping and single-cell transcriptomics allow identification of circulating TRM-like cells which correlate with liver-stage immunity and vaccine-induced protection from malaria

Protection from liver-stage malaria requires high numbers of CD8+ T cells to find and kill Plasmodium-infected cells. A new malaria vaccine strategy, prime-target vaccination, involves sequential viral-vectored vaccination by intramuscular and intravenous routes to target cellular immunity to the li...

詳細記述

書誌詳細
主要な著者: Noe, A, Datoo, M, Flaxman, A, Jenkin, D, Bellamy, D, Makinson, R, Morter, R, Ramos Lopez, F, Sheridan, J, Voukantsis, D, Prasad, N, Hill, A, Ewer, K, Spencer, A
フォーマット: Journal article
言語:English
出版事項: Frontiers Media 2022