Multiscale simulations suggest a mechanism for the association of Dok7’s PH domain with PIP-containing membranes
Dok7 is a peripheral membrane protein that is associated with the MuSK receptor tyrosine kinase. Formation of the Dok7/MuSK/membrane complex is required for the activation of MuSK. This is a key step in the complex exchange of signals between neuron and muscle, which lead to neuromuscular junction f...
| Main Authors: | , , |
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| 格式: | Journal article |
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Public Library of Science
2016
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