Multiscale simulations suggest a mechanism for the association of Dok7’s PH domain with PIP-containing membranes
Dok7 is a peripheral membrane protein that is associated with the MuSK receptor tyrosine kinase. Formation of the Dok7/MuSK/membrane complex is required for the activation of MuSK. This is a key step in the complex exchange of signals between neuron and muscle, which lead to neuromuscular junction f...
| المؤلفون الرئيسيون: | , , |
|---|---|
| التنسيق: | Journal article |
| منشور في: |
Public Library of Science
2016
|