Multiscale simulations suggest a mechanism for the association of Dok7’s PH domain with PIP-containing membranes

Multiscale simulations suggest a mechanism for the association of Dok7’s PH domain with PIP-containing membranes

Dok7 is a peripheral membrane protein that is associated with the MuSK receptor tyrosine kinase. Formation of the Dok7/MuSK/membrane complex is required for the activation of MuSK. This is a key step in the complex exchange of signals between neuron and muscle, which lead to neuromuscular junction f...

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Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Buyan, A, Kalli, A, Sansom, M
Формат:	Journal article
Хэвлэсэн:	Public Library of Science 2016

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