Peripheral burst of tumor-specific cytotoxic T lymphocytes and infiltration of metastatic lesions by memory CD8+ T cells in melanoma patients receiving interleukin 12.

Systemic effects on T-cell-mediated antitumor immunity, on expression of T-cell adhesion/homing receptors, and on the promotion of T-cell infiltration of neoplastic tissue may represent key steps for the efficacy of immunological therapies of cancer. In this study, we investigated whether these proc...

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Bibliographic Details
Main Authors: Mortarini, R, Borri, A, Tragni, G, Bersani, I, Vegetti, C, Bajetta, E, Pilotti, S, Cerundolo, V, Anichini, A
Format: Journal article
Language:English
Published: 2000