The assembly of large BACs by in vivo recombination.

We have developed a method for recombining bacterial artificial chromosomes (BACs) and P1 artificial chromosomes (PACs) containing large genomic DNA fragments into a single vector using the Cre-lox recombination system from bacteriophage P1 in vivo. This overcomes the limitations of in vitro methods...

Полное описание

Библиографические подробности
Главные авторы: Mejía, J, Larin, Z
Формат: Journal article
Язык:English
Опубликовано: 2000

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