Mechanisms of substrate processing during ER-associated protein degradation
Maintaining proteome integrity is essential for long-term viability of all organisms and is overseen by intrinsic quality control mechanisms. The secretory pathway of eukaryotes poses a challenge for such quality assurance as proteins destined for secretion enter the endoplasmic reticulum (ER) and b...
Main Authors: | , , |
---|---|
格式: | Journal article |
语言: | English |
出版: |
Springer Nature
2023
|