Mechanisms of substrate processing during ER-associated protein degradation

Mechanisms of substrate processing during ER-associated protein degradation

Maintaining proteome integrity is essential for long-term viability of all organisms and is overseen by intrinsic quality control mechanisms. The secretory pathway of eukaryotes poses a challenge for such quality assurance as proteins destined for secretion enter the endoplasmic reticulum (ER) and b...

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Dettagli Bibliografici
Autori principali:	Christianson, JC, Jarosch, E, Sommer, TJ
Natura:	Journal article
Lingua:	English
Pubblicazione:	Springer Nature 2023

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