Mechanisms of substrate processing during ER-associated protein degradation
Maintaining proteome integrity is essential for long-term viability of all organisms and is overseen by intrinsic quality control mechanisms. The secretory pathway of eukaryotes poses a challenge for such quality assurance as proteins destined for secretion enter the endoplasmic reticulum (ER) and b...
Principais autores: | Christianson, JC, Jarosch, E, Sommer, TJ |
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Formato: | Journal article |
Idioma: | English |
Publicado em: |
Springer Nature
2023
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