Structures of SAS-6 suggest its organization in centrioles.

Centrioles are cylindrical, ninefold symmetrical structures with peripheral triplet microtubules strictly required to template cilia and flagella. The highly conserved protein SAS-6 constitutes the center of the cartwheel assembly that scaffolds centrioles early in their biogenesis. We determined th...

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Bibliographic Details
Main Authors: van Breugel, M, Hirono, M, Andreeva, A, Yanagisawa, H, Yamaguchi, S, Nakazawa, Y, Morgner, N, Petrovich, M, Ebong, I, Robinson, C, Johnson, C, Veprintsev, D, Zuber, B
Format: Journal article
Language:English
Published: 2011