Functional heterogeneity and high frequencies of cytomegalovirus-specific CD8(+) T lymphocytes in healthy seropositive donors

Functional heterogeneity and high frequencies of cytomegalovirus-specific CD8(+) T lymphocytes in healthy seropositive donors

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Human cytomegalovirus (HCMV) infection is largely asymptomatic in the immunocompetent host, but remains a major cause of morbidity in immunosuppressed individuals. Using the recently described technique of staining antigen-specific CD8+ T cells with peptide-HLA tetrameric complexes, we have demonstr...

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Bibliografiska uppgifter
Huvudupphovsmän:	Gillespie, G, Wills, MR, Appay, V, O'Callaghan, C, Murphy, M, Smith, N, Sissons, P, Rowland-Jones, S, Bell, J, Moss, P
Materialtyp:	Journal article
Språk:	English
Publicerad:	2000

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