Understanding the free energy landscapes and self-limiting assembly of DNA origamis using coarse-grained modelling

<p>Coarse-grained modelling of DNA nanostructures allows their structural, mechanical and thermodynamic properties to be characterised. In this thesis, we illustrated how coarse-grained modelling combined with umbrella sampling can be applied to compute the free energy landscapes of large DNA...

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Bibliographic Details
Main Author: Wong, CK
Other Authors: Doye, J
Format: Thesis
Language:English
Published: 2022