Interleukin-22 promotes phagolysosomal fusion to induce protection against Salmonella enterica Typhimurium in human epithelial cells

Interleukin-22 promotes phagolysosomal fusion to induce protection against Salmonella enterica Typhimurium in human epithelial cells

Intestinal epithelial cells (IECs) play a key role in regulating immune responses and controlling infection. However, the direct role of IECs in restricting pathogens remains incompletely understood. Here, we provide evidence that IL-22 primed intestinal organoids derived from healthy human induced...

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Bibliografiske detaljer
Main Authors:	Forbester, J, Lees, E, Goulding, D, Forrest, S, Yeung, A, Speak, A, Clare, S, Coomber, E, Mukhopadhyay, S, Kraiczy, J, Schreiber, F, Lawley, T, Hancock, R, Uhlig, H, Zilbauer, M, Powrie, F, Dougan, G
Format:	Journal article
Sprog:	English
Udgivet:	National Academy of Sciences 2018

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