High-resolution structures of bacterially expressed soluble human CD59.

CD59 is a membrane-bound glycoprotein that protects host cells from lysis by inhibiting the terminal pathway of complement, preventing the formation and insertion of the membrane attack complex (MAC). Crystals of bacterially expressed and nonglycosylated recombinant soluble human CD59 have been obta...

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Autors principals: Leath, K, Johnson, S, Roversi, P, Hughes, T, Smith, R, Mackenzie, L, Morgan, B, Lea, S
Format: Journal article
Idioma:English
Publicat: 2007