Molecular dynamics simulations of the ligand-binding domain of an N-methyl-D-aspartate receptor.
The mechanism of partial agonism at N-methyl-D-aspartate receptors is an unresolved issue, especially with respect to the role of protein dynamics. We have performed multiple molecular dynamics simulations (7 x 20 ns) to examine the behavior of the ligand-binding core of the NR1 subunit with a serie...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2006
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