Effects of troponin C isoform on the action of the cardiotonic agent EMD 57033.

The effects of the cardiotonic potentiator EMD 57033 on different TnC (troponin C) isoforms were investigated. Endogenous skeletal TnC was extracted from glycerinated, permeabilized rabbit psoas fibres and replaced with either purified native rabbit psoas TnC (fast TnC) or human recombinant cTnC (ca...

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Autors principals: Lipscomb, S, Preston, L, Robinson, P, Redwood, C, Mulligan, I, Ashley, C
Format: Journal article
Idioma:English
Publicat: 2005