Proteomic analysis of tendon extracellular matrix reveals disease stage-specific fragmentation and differential cleavage of COMP (cartilage oligomeric matrix protein).

During inflammatory processes the extracellular matrix (ECM) is extensively remodeled, and many of the constituent components are released as proteolytically cleaved fragments. These degradative processes are better documented for inflammatory joint diseases than tendinopathy even though the pathoge...

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Autors principals: Dakin, S, Smith, R, Heinegård, D, Önnerfjord, P, Khabut, A, Dudhia, J
Format: Journal article
Idioma:English
Publicat: 2014