Role of tissue transglutaminase in gliadin binding to reticular extracellular matrix and relation to coeliac disease autoantibodies.

On different tissue sections, binding of gliadin to reticular matrix components was observed which was Ca2+-dependent, inhibited by Cu2+ and Zn2+ ions, by putrescine, and by preincubation with antibodies against tissue transglutaminase (tTG) suggesting that binding of gliadin is mediated by tTG. tTG...

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Bibliographic Details
Main Authors: Uhlig, H, Osman, A, Tanev, I, Viehweg, J, Mothes, T
Format: Journal article
Language:English
Published: 1998