Do NMDA antagonists protect against cerebral ischemia: are clinical trials warranted?

An accumulation of experimental data suggests that N-methyl-D-aspartate (NMDA) receptor antagonists will prevent ischemic neuronal injury following transient global ischemia and reduce infarct volumes following focal ischemic insults. The excitotoxic hypothesis states that the excitatory amino acid...

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Bibliographic Details
Main Author: Buchan, A
Format: Journal article
Language:English
Published: 1990