Histone methyltransferase inhibitors: orally bioavailable, fast acting molecules with activity against different human malaria species.

Current antimalarials are under continuous threat due to the relentless development of drug resistance by malaria parasites. We previously reported promising in vitro parasite killing activity with the histone methyltransferase inhibitor BIX-01294 and its analogue TM2-115. Here we further characteri...

詳細記述

書誌詳細
主要な著者: Malmquist, N, Sundriyal, S, Caron, J, Chen, P, Witkowski, B, Menard, D, Suwanarusk, R, Renia, L, Nosten, F, Jiménez-Díaz, M, Angulo-Barturen, I, Martínez, MS, Ferrer, S, Sanz, L, Gamo, F, Wittlin, S, Duffy, S, Avery, V, Ruecker, A, Delves, M, Sinden, R, Fuchter, M, Scherf, A
フォーマット: Journal article
言語:English
出版事項: 2014