Comparison of a limiting dilution assay and ELISpot for detection of memory B-cells before and after immunisation with a protein-polysaccharide conjugate vaccine in children

In the present study, the limiting dilution assay (LDA) and the ELISpot are compared in their ability to detect serogroup C meningococcal (MenC)-specific memory B-cells in peripheral blood of 12 month old children, after 3-dose priming with serogroup C meningococcal conjugate vaccine (MenCV) in infa...

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Bibliographic Details
Main Authors: Blanchard-Rohner, G, Galli, G, Clutterbuck, E, Pollard, A
Other Authors: Association of Medical Laboratory Immunologists
Format: Journal article
Language:English
Published: Elsevier 2010
Subjects: