Fundamental biochemistry of the early N-glycosylation pathway
<p>Oligosaccharides destined for use as N-linked glycans are synthesised on phosphorylated dolichols in the endoplasmic reticulum (ER) by a series of glycosyltransferase enzymes known as ALG proteins. Mutations in any of these synthesis enzymes can lead to severe, multisystem syndromes known a...
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| Format: | Thesis |
| Language: | English |
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2024
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