Bench-stable transfer reagent facilitates the generation of trifluoromethyl-sulfonimidamides

Sulfonimidamides are an emerging bioisosteric replacement in medicinal chemistry projects, and therefore new chemistries are necessary to access this functionality. The general synthesis of CF3-sulfonimidamides from an activated bench-stable transfer reagent is described. A diverse reaction scope is...

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Détails bibliographiques
Auteurs principaux: Wright, M, Martínez-Lamenca, C, Leenaerts, J, Brennan, P, Trabanco, A, Oehlrich, D
Format: Journal article
Langue:English
Publié: American Chemical Society 2018