In vitro and in vivo activity of ML302F: a thioenolate inhibitor of VIM-subfamily metallo β-lactamases
The thioenol ML302F was recently identified as an inhibitor of class B metallo-β-lactamases (MBLs). We assessed the activity of ML302F when combined with meropenem (MEM) against 31 carbapenem resistant Gram-negative clinical isolates. Minimum inhibitory concentrations of MEM:ML302F were determined a...
| প্রধান লেখক: | , , , , , , |
|---|---|
| বিন্যাস: | Journal article |
| প্রকাশিত: |
Royal Society of Chemistry
2015
|