Assessment of the nlmixr R package for population pharmacokinetic modeling: a metformin case study
<br><strong>Aim<br></strong>nlmixr offers first-order conditional estimation (FOCE), FOCE with interaction (FOCEi) and stochastic approximation estimation-maximisation (SAEM) to fit nonlinear mixed-effect models (NLMEM). We modelled metformin's pharmacokinetic data using...
Main Authors: | , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Wiley
2022
|