Assessment of the nlmixr R package for population pharmacokinetic modeling: a metformin case study

Assessment of the nlmixr R package for population pharmacokinetic modeling: a metformin case study

<br><strong>Aim<br></strong>nlmixr offers first-order conditional estimation (FOCE), FOCE with interaction (FOCEi) and stochastic approximation estimation-maximisation (SAEM) to fit nonlinear mixed-effect models (NLMEM). We modelled metformin's pharmacokinetic data using...

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Bibliographic Details
Main Authors:	Mak, WY, Ooi, QX, Cruz, CV, Looi, I, Yuen, KH, Standing, JF
Format:	Journal article
Language:	English
Published:	Wiley 2022

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