The Interplay between Feedback and Buffering in Cellular Homeostasis

Buffering, the use of reservoirs of molecules to maintain concentrations of key molecular species, and negative feedback are the primary known mechanisms for robust homeostatic regulation. To our knowledge, however, the fundamental principles behind their combined effect have not been elucidated. He...

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Bibliographic Details
Main Authors: Hancock, E, Ang, J, Papachristodoulou, A, Stan, G
Format: Journal article
Language:English
Published: Elsevier 2017